Aspirin Resistance

Dr. Eric Powers – Cardiology, MUSC

Dr. Eric Powers:  Aspirin resistance can be measured with platelet function studies.  There are some platelet function studies, which are the traditional studies, which take quite a long time to get back, quite expensive, and quite resource intensive.  But there are, now, new devices on the market which can actually measure platelet function very quickly. 

One of the things we’re interested in is a point of care approach, where you’ll take a patient whose gotten aspirin, clopidogrel, whatever, or not, to measure their platelet function at the point of care.  The test can be done very quickly, and then you can make a decision about what to do about it.  What to do about it is also something we’re currently studying.  The idea is that if someone is resistant to aspirin, and that can be measured, again, with one of these point of care tests, if they’re resistant to aspirin, they should get some other anti-platelet therapy:  be it clopidogrel, be it a IIb/IIIa receptor block, or whatever it turns out to be.