MUSC Heart Transplant Program

musc transplant center

Transplant Selection Criteria

In order to be a good candidate for a heart transplant, patients must have end-state heart disease with significant risk of mortality within one year, including:

  • Severely reduced left ventricular ejection fraction
  • Severely reduced functional capacity
  • Poor progress based on cardiopulmonary stress test
  • A heart failure survival score indicating high risk
  • Inoperable benign primary cardiac tumors
  • Inoperable coronary artery disease with intractable angina
  • Refractory ventricular arrhythmias

Patients having the following conditions are not good candidates for a heart transplant:

  • Fixed pulmonary hypertension
  • Severe, chronic disabling diseases
  • Severe, irreversible, chronic impairment of other vital organs, such as kidneys, intestines, liver, lungs or central nervous system
  • Recent or uncontrolled malignancy
  • Symptomatic, severe peripheral, visceral, carotid or cerebrovascular disease that cannot be corrected
  • Malignant hypertension
  • Inability to discontinue recreational drug, tobacco or alcohol use
  • Active mental illness that interferes with medical treatment compliance
  • Psychosocial instability, lack of social or family support, ongoing noncompliance with medical treatment
  • 70 years old or older
  • Pulmonary infarction within the past six weeks
  • Very brittle diabetes or diabetes with end organ damage
  • Major chronic disabling diseases, such as arthritis, stroke, neurological disease, severe inflammatory or collagen vascular disease
  • Recent or uncontrolled peptic ulcer disease
  • Active, but treatable infection (temporary)
  • Morbid obesity
  • HIV seroconversion

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