In addition to a thorough physical exam and testing, patients undergo Human Leukocyte Antigen (HLA) typing to determine if the make-up of their immune system’s cells. This is necessary to ensure that their cells are compatible with a donor’s cells. If the recipient’s HLA type is different from the donor’s, the recipient’s immune system may see the new bone marrow as foreign and may attack or reject it. Or, the donor’s bone marrow may see the recipient’s as foreign and attack body cells. Along with HLA typing, bone and marrow transplant patients will undergo the following tests: - Bone marrow aspirate & biopsy, including a lumbar puncture
- Echocardiogram
- EKG
- Pulmonary function test
- PET or CT scans
- Glomerular filtration rate (GFR) renal study
- Iiodine meta-ioodobenzylguanidine (MIBG) scan for tumors
- Bone scan
- Audiogram
- Lab work
- Central venous line placement (catheter placement)
- 24-hour urine collection
Patients will also consult with a pediatric dentist and pediatric cardiology, radiation and pulmonary physicians. | 
