Alternate Medications

Agent

Dose

Efficacy

Time Required to be Effective

Common Side Effects

Uncommon Side Effects

Methotrexate

10-20 mg/week

+++

1-3 months

N, Diarrhea, Headache

Cirrhosis, ILD

Azathioprine

1-3 mg/kg/day

+

1-3 months

N, V, Diarrhea, WBC

Pancreatitis

Hydroxychloroquine*

100-400 ml/day

+

6 months

N

Cornea, Retinal Damage

Chlorambucil

4-12 mg/day

++

1-3 months

N, WBC , Rash, PLTS

Pentoxifylline

1200 mg/day

++

1-3 months

N, Dyspnea, Diarrhea

Inhaled Corticosteroids

1600g/day

+

1-3 months

Oral Candidasis