Alternate Medications | Agent | Dose | Efficacy | Time Required to be Effective | Common Side Effects | Uncommon Side Effects | Methotrexate | 10-20 mg/week | +++ | 1-3 months | N, Diarrhea, Headache | Cirrhosis, ILD | Azathioprine | 1-3 mg/kg/day | + | 1-3 months | N, V, Diarrhea, WBC  | Pancreatitis | Hydroxychloroquine | 100-400 ml/day | + | 6 months | N | Cornea, Retinal Damage | Chlorambucil | 4-12 mg/day | ++ | 1-3 months | N, WBC , Rash, PLTS | | Pentoxifylline | 1200 mg/day | ++ | 1-3 months | N, Dyspnea, Diarrhea | | Inhaled Corticosteroids | 1600 g/day | + | 1-3 months | Oral Candidasis | |
 Physician Information Page | Legend | + | Fair | ++ | Good | +++ | Very Good | N | Nausea | V | Vomiting | ILD | Interstitial lung disease | WBC | Depression of white blood cell count | PLTS | Depression of platelet count | | Cannot be used in G6PD deficient patients, need baseline eye exam |
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