In this cancer podcast, Dr. Carolyn Reed, Chief of General Thoracic Surgery at MUSC, discusses symptoms of esophageal cancer, focusing on gastric reflux leading to Barrett’s Esophagus. She explains why reflux occurs in some people and discusses the controversy over the most efficacious way to prevent and treat gastric and bile reflux into the esophagus. Dr. Reed concludes by explaining the sequence from reflux induced Barrett’s Esophagus to esophageal cancer.