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Home > Multiple Sclerosis > About Multiple Sclerosis > Cognitive Impairment
Cognitive Impairments

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Arrow Symptoms

Arrow  Cognitive Impairments

Arrow  MS Subtypes and Frequency

Arrow  Causes of MS

Arrow  Diagnosing MS

Introduction
(Adapted from Rosalind C. Kalb, PhD)

Multiple sclerosis is a disease that causes damage to nerve fibers in the brain and spinal cord. Because demyelination occurs in the brains of most people who have MS, cognitive functions can be affected. It is only within the last 10 years or so that cognitive impairment has been acknowledged and studied by MS professionals. It remains a difficult topic for many people with MS and their doctors to think about or discuss. Like the emotional aspects of MS, however, cognitive changes have the potential to affect any and all family issues discussed in this book.

Research has shown that approximately half of people with MS have no apparent cognitive changes. Approximately 40 percent have cognitive changes that can be measured by psychological tests but which are only mildly or moderately disruptive of everyday activities (e.g., someone who has to write everything down because of memory problems). A small proportion of people with MS, probably no more than 5 percent to 10 percent, have cognitive changes that are so severe that they seriously disrupt day-to-day life (e.g., a person who cannot manage personal finances because of extreme confusion and disorganized thinking).

What exactly is meant by "cognition?" The word comes from the Latin verb "to think" and refers to the "higher" brain functions such as memory and reasoning in contrast to more primitive functions such as sensation (e.g., vision, hearing) and motor function (e.g., strength, coordination). In MS, a number of these "higher" functions may be affected. The ones most commonly affected are:

Research on the Cognitive Effects of MS

Arrow Cortical/SubCortical Disease Burden And Cognitive Impairment In Multiple Sclerosis
Arrow Performance Of Delayed Intentions In Multiple Sclerosis
Arrow Cognitive Function In P/P & T/P Multiple Sclerosis
Arrow Cognitive Impairment In Multiple Sclerosis: Changes In Normal Appearing Brain Tissue
Arrow MRI Study Of Frontal Lobe Dementia In MS
Arrow Magnetization Transfer Histogram Study Of Normal-Appearing Brain Tissue In MS
Arrow Correlations Between Clinical And MRI Involvement In Multiple Sclerosis: Assessment Using T1, T2 And MT Histograms
Arrow Brain Involvement In Systemic Immune Mediated Diseases: Magnetic Resonance And Magnetization Transfer Imaging Study
Arrow Magnetic Resonance Relaxation Time Mapping In Multiple Sclerosis: Normal-Appearing White Matter And The "Invisible" Lesion Load
Arrow Brain MRI Correlates Of Magnetization Transfer Imaging Metrics In MS
Arrow MRI And Magnetization Transfer Imaging - Changes In The Brain And Cervical Cord In Devic's NeuroMyelitis Optica
Arrow Gadolinium Enhancement Increases MRI Sensitivity For Multiple Sclerosis Disease Activity
Arrow The Evolution Of The Concentric Lesions Of Atypical Multiple Sclerosis On MRI

Page last updated: 02/01/06
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