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Dr. Romagnuolo, M.D., is an Associate Professor of Medicine in the Division of Gastroenterology and Hepatology, and is cross-appointed to the Department of Biometry, Bioinformatics and Epidemiology, at the Medical University of South Carolina. He is also the Director of Clinical Research for Gastroenterology and Hepatology. Dr. Romagnuolo received his medical degree (M.D.) from the University of Toronto in 1994. Dr. Romagnuolo has also completed an MSc degree in Epidemiology and Biostatistics and a two-year advanced endoscopy fellowship, including ERCP (endoscopic retrograde cholangiopancreatography) and endoscopic ultrasound (EUS), at McGill University and the Medical University of South Carolina. He is board certified in Gastroenterology.

Dr. Romagnuolo is a member of several organizations, including Canadian Association of Gastroenterology (CAG); American Gastroenterological Association (AGA); American Society of Gastrointestinal Endoscopy (ASGE); American College of Gastroenterology (ACG); and the American College of Physicians (ACP). He sat on the Randomized Controlled Trials Committee of the Canadian Institutes for Health Research (CIHR) and the ASGE Research Committee as well as the CAG endoscopy committee each for several years. He co-directed the international ASGE postgraduate endoscopy course (2006)and was on the scientific organizing committee for the World Congress of Gastroenterology in 2005. He is also on the following MUSC Committees: Chair, Digestive Disease Center Research Committee; Member, GI/Hepatology Fellowship Education Committee; and has been a member of three Master’s Thesis Committees. He is a member of the ASGE Quality (in Endoscopy) Task Force.

Dr. Romagnuolo has received numerous awards and honors during his career, including Fellow of the Royal College of Physicians and Surgeons of Canada (FRCPC); Endoscopy Clinical Research Fellowship from Alberta Heritage Foundation for Medical Research (AHFMR); Young Investigator Award from CAG and CIHR; Population Health Young Investigator Award from AHFMR; and ASGE/SAGES Ethicon Award for NOTES (natural orifice transluminal endoscopy surgery) Research. He was the research supervisor of two recipients (2003 and 2004) of the Canadian Society of Clinical Investigation (CSCI) award. He has mentored students in obtaining funding from the Center for Health Disparities Research. He was honored as a "Fellow" of the ASGE and of the ACG. He received the Outstanding Faculty Research Presentation Award in 2007. Dr. Romagnuolo received the prestigious ASGE Mid-career Endoscopic Mentoring Award in 2008.

Dr. Romagnuolo’s research interests are in clinical trials, economic analysis, and outcomes research in endoscopy, especially ERCP and EUS, biliopancreatic diseases, gastrointestinal malignancy and NOTES. He has over 50 peer-reviewed papers published or in press, in addition to five book chapters and well over 100 abstracts. He is the MUSC site-PI (principal investigator) of the NIH-funded ERCP therapy for suspected sphincter of Oddi dysfunction (SOD).