
Associate Professor, Department of Neurosciences Associate Professor, Department of Psychiatry and Behavioral Sciences |
EDUCATION | Birmingham Southern College, Birmingham, AL | B.S. | 1980 | Biology | | University of Texas, Austin, TX | Ph.D. | 1988 | Pharmacology | | University of Florida, Gainesville, GL | Postdoctoral | 1989 | Neuropharmacology |
PROFESSIONAL EXPERIENCE | 1980-1982 | Research Assistant, Department of Pharmacology, University of Alabama, Birmingham, AL | | 1983-1987 | Graduate Student, Department of Pharmacology & Toxicology, College of Pharmacy, University of Texas, Austin, TX | | 1988-1989 | Postdoctoral Fellow, Department of Pharmacology & Therapeutics, College of Medicine, University of Florida, Gainesville, FL | | 1989-1994 | Assistant Research Scientist, Department of Pharmacology & Therapeutics, College of Medicine, University of Florida, Gainesville, FL | | 1994-1999 | Assistant Professor, Department of Pharmacology & Therapeutics, Louisiana State University Medical Center, Shreveport, LA | | 1999 | Associate Professor, Department of Pharmacology &Therapeutics, Louisiana State University Medical Center, Shreveport, LA | | 1999-present | Associate Professor, Department of Neurosciences and Department of Psychiatry & Behavioral Sciences, MUSC, Charleston, SC |
AWARDS AND HONORS | 1989 | Postdoctoral Training Fellowship, National Institute on Aging | | 1989 | International Society of Neurochemistry Young Scientist Travel Award | | 1990-1995 | NIAAA K21 Scientist Development Award | | 1991 | International Society of Neurochemistry Young Scientist Travel Award | | 1998-2004 | Research Society on Alcoholism Education Committee | | 1999-present | Board of Reviewing Editors; Alcoholism: Clinical and Experimental Research | | 2001-present | NIAAA Special Emphasis Study Section (AA-1) |
PUBLICATIONS (2006-present) Carpenter-Hyland E & Chandler LJ. Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines. European Journal of Neuroscience 24(12):3496-3506, 2006. Chandler LJ, Carpenter-Hyland E, Hendricson AW, Maldve RE, Morrisett RA, Zhou FC, Sari Y, Bell R & Szumlinski KK. Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. Alcoholism: Clinical and Experimental Research 30(2):368-376, 2006. Lapish CC, Seamans JK & Chandler LJ. Glutamate-dopamine cotransmission and reward processing in addiction. Alcoholism: Clinical & Experimental Research 30(9):1451-1465, 2006. Carpenter-Hyland EP & Chandler LJ. Adaptive plasticity of NMDA receptors and dendritic spines: Implications for enhanced vulnerability of the adolescent brain to alcohol addiction. Pharmacology, Biochemistry & Behavior 86(2):200-208, 2007. Hajjhussein H, Suvarna NU, Gremillion C, Chandler LJ & O'Donnell JM. Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures. Brain Research 1149:58-68, 2007. Mulholland PJ & Chandler LJ. The Plasticity of Alcohol Addiction Suggest Novel Approaches to Pharmacological Intervention. In Translation of Addictions Science into Practice: Update and Future Directions, Miller PM, Kavanagh D (Eds). Elsevier-Pergamon, New York, NY, 2007. Tu Y, Kroener S, Abernathy K, Lapish C, Seamans J, Chandler LJ & Woodward JJ. Ethanol inhibits persistent activity in prefrontal cortical neurons. Journal of Neuroscience 27(17):4765-4775, 2007. |