Significant Events in the History of MUSC | The MUSC Seal | 
| On December 20, 1823, a Charter was granted for a medical college (legislation provided no funding, proprietary school) at the request of the Medical Society of South Carolina. |
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1824 | Opening (Medical College of South Carolina) |
1825 | 1st graduating class (Eli Geddings, the first of 5 graduates) |
1826 | 1st permanent building (on Queen Street, at Franklin) |
1832 | School Split - Medical College of South Carolina and Medical College of the State of South Carolina |
1839 | Reconciliation between the two factions under the name Medical College of the State of South Carolina |
1850 | First Roper Hospital building construction on Queen Street (medical college teaching hospital) |
1852 | Roper Hospital "more or less complete" |
1854 | Roper Hospital used for yellow fever epidemic |
1856 | Roper Hospital in regular use |
1861 | School closed due to War (after graduation in March 1861) |
1865 | School reopened with faculty returned from War |
1881 | Pharmacy School created |
1882 | Pharmacy School opened |
1883 | School of Nursing opened |
1886 | Charleston earthquake damage closes Roper Hospital |
1890 | 3-year graded course established for the College of Medicine |
1894 | Medical school opened to women (announced in catalog) |
1898 | First women admitted |
1899 | 4-year graded course established for the College of Medicine |
1901 | First women graduated: Love Rosa Hirschmann, M.D. (Mrs. Robert Joseph Gantt) Emilie Melanie Viett, M.D. (Mrs. Henry Rundlett) |
1904 | City Hospital's "South Carolina Training School for Nurses" became "Roper Hospital Training School for Nurses" |
1906 | Roper Hospital new building "Old Roper" (corner of Calhoun and Lucas Streets) |
1913 | Medical College of the State of South Carolina became a state institution |
1914 | New building - campus moved to present site |
1919 | Roper Hospital Training School for Nurses became the School of Nursing of the Medical College of the State of South Carolina. |
1924 | Centennial Celebration |
1943 | "New" Roper Hospital construction began |
1950 | First students admitted to Graduate Studies Program |
1950 | Board of Trustee titles change from President and Vice President to Chairman and Vice Chairman |
1952 | Name changed back to original name: Medical College of South Carolina |
1953 | S. C. General Assembly approved the establishment of a Dental School |
1955 | Medical College Hospital opened - prior to 1955, Roper Hospital served as the teaching hospital for the medical college |
1959 | The 1906 "Old" Roper Hospital building closed |
1965 | School of Graduate Studies officially founded |
1965 | First African-American student admitted to College of Medicine |
1966 | School of Allied Health Sciences founded |
1966 | Organization of the Board into four subcommittees in December 1966 |
1966 | College of Nursing diploma program became baccalaureate degree program |
1967 | First class enrolled in School of Dental Medicine |
| 1969 | College of Allied Health Sciences (1969-1986) |
1969 | University status attained name change to Medical University of South Carolina and schools within the university changed to "colleges" |
1969 | Hospital Strike of ninety-nine days (March 20 - June 27) |
1970 | Family Practice Program established. One of the first in the nation. Dr. Hiram B. Curry was named Professor and Chairman of the new department. |
1971 | First African-American student graduated from the College of Medicine |
1971 | First class graduated from the College of Dental Medicine |
1974 | Sesquicentennial Celebration |
1977 | Faculty-Alumni House (Wickliffe) property acquired (including Guest House), with funds donated by Margaret Wickliffe of West Union, SC |
1980 | 25th Anniversary of the Medical University Hospital opening |
1986 | MUSC College of Health Related Professions (1986-1993) |
1993 | Establishment of the MUSC College of Health Professions |